Constant meditation on Krishna eliminates material anxiety and perfects human life through devotional association.Listen — Srila Prabhupada Uvaca
Śrīmad-Bhāgavatam 1.15.29 — December 7, 1973, Los Angeles 731207SB-LOS ANGELES [27:33 Minutes] SB-01.15.29_731207SB-LOS ANGELES Pradyumna: Translation: "Arjuna's constant remembrance of the lotus feet of Lord Śrī Kṛṣṇa rapidly increased his devotion, and as a result all the trash in his thoughts subsided." [SB 1.15.29]
Prabhupāda: So material existence means full of anxieties. This is the sum and substance of material existence. Everyone is full of anxieties, not only humans. Just like Karandhara was speaking, there are so many bad news.
What is that? Where is Karandhara? Karandhara: Energy crisis, food shortage.
Prabhupāda: Yes, energy crisis, food shortage, and what else? Karandhara: Economic turmoil.
Prabhupāda: Hmm. And even Mr. Nixon is in such exalted post, he's also full of anxieties, when he'll be kicked out. You see.
So find out any man who is not in anxiety. Not only human being but also animals, birds, beasts—everyone. That is the symptom of material existence, anxieties. So spiritual life means anxiety-less.
This is the difference between material life and spiritual life. Brahma-bhūtaḥ prasannātmā [Bg. 18.54]. In the Bhagavad-gītā it is described what is spiritual life. As soon as you are identified with the Absolute Truth, Brahman, then symptoms will be prasannātmā, jubilation: "Oh, I do not belong to this material world; I belong to the spiritual world.